Course Unit D-U1 Innovative products design
Course Unit D-U3 Alternative pharmaceutical products design
The concepts of Sustainable Chemistry. The 12 Principles of Green Chemistry. Voluntary and compulsory regulation of chemical products. A life-cycle approach to alternative green products. The general features of a green product and the most critical fields requiring the development of alternative green products.
The Presidential Green Chemistry Challenge Award will be described and some of the most successful innovations awarded the Prize will be critically examined. Some case examples will be deepened. Green Pesticides will be presented and discussed as examples of successful alternative products.
- Teacher: Emilio Tagliavini
Course Unit D-U1 Innovative products design and
Course Unit D-U3 Alternative pharmaceutical products design
- Historical and introductory concepts on Structure-Activity and Structure-Toxicity relationships.
- 2D molecular representations: linear notation and connection tables. Bit-string representation of molecules: structural keys and hashed fingerprints. Similarity and Tanimoto coefficient. 3D molecular representations. Practical exercises using open software.
- Molecular descriptors: theory and practical exercises with open software
- QSAR and QSPR analysis. Building of a linear relationship of activity against values of molecular descriptors for a small set of similar compounds using a spreadsheet.
- Lecturer: Luca Evangelisti
Course Unit D-U1 Innovative products design
Course Unit D-U2 Applied new products
1. Structure of products : Properties of particulate materials. Liquid and gels properties: rheology and texture. Correlation among structures and behavior in application
2. Components of products. Active ingredients. Functional additives: surfactants and polymers
3. Formulation of products. Design of formulations and experimental designs
4. Unit operations and processes for preparation of products.- Lecturer: Santiago Esplugas
Course Unit D-U2 Applied new products
1. Origen of raw materials
2. Preparation assembly and structuring of raw materials
Conventional foods
Novel foods
3. Unit operations in food industry
4. Thermal and non-Thermal preservation technologies
5. Overview of HACCP (Hazard Analysis and Critical Control Points) and packaging of foods
- Lecturer: Carmen Gonzalez
Course Unit D-U2 Applied new products
Acquire the basic theoretical knowledge to understand the applications of different materials, as determined by their structure and physical/chemical properties.
Understand how different materials respond to different technological requirements.
At the end of the module the student is expected to be able to:
1. Understand and apply the information given in the recommended reading and study resources focused on commonly used materials.
2. Acquire the knowledge required to develop experimental skills for materials work.
3. Apply theoretical knowledge to practical situations, using mathematical and graphic models and other appropriate tools to solve basic problems in materials science.
- Lecturer: Merce Segarra
Course Unit D-U3 Alternative pharmaceutical products design
Gain an overview of the different methodologies currently applied to the pharmaceutical industry to design and develop new drugs, from the identification of new chemical entities to register, being aware of such a complex multidisciplinary nature of this area of research..
At the end of the module the student is expected to be able to:
1. Assimilate the usefulness and the predictive value of QSAR and Docking methodologies and the scope of computer-aided drug design
2. Visualise and rationalise protein-ligand interactions
3. Understand the different approaches to predict the affinity between a ligand and a receptor- Lecturer: Carolina Estarellas